pentobarbital will lessen the level or influence of ritonavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
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pentobarbital will lessen the level or result of nitrendipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Mysterious.
pentobarbital boosts toxicity of ifosfamide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers may well raise the metabolism of ifosfamide to its active alkylating metabolites.
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Contraindicated (one)pentobarbital will reduce the extent or outcome of cariprazine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is answerable for the development and elimination of cariprazine's active metabolites.
pentobarbital will reduce the level or outcome of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Potent or reasonable CYP3A4 inducers may possibly maximize charge of diazepam elimination; consequently, efficacy of diazepam can be decreased.
pentobarbital will reduce the level or effect of amiodarone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital decreases effects of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Coadministration of CYP3A4 inducers may well decrease sufentanil levels and efficacy, probably precipitating withdrawal syndrome in sufferers which have designed Actual physical dependence to sufentanil. Discontinuation of concomitantly utilized CYP3A4 inducers may possibly maximize sufentanil plasma concentration.
pentobarbital will decrease the level or outcome of erlotinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lower the extent or effect of zolpidem by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.
pentobarbital will decrease the extent or effect of roflumilast by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration not advised; strong cytochrome P450 enzyme inducers lower systemic exposure to roflumilast and should reduce the therapeutic performance
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pentobarbital will minimize the level or result of propafenone by influencing is nembutal a barbiturate hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Not known.